Incidence and Factors Associated With Acne in Transgender Adolescents on Testosterone: A Retrospective Cohort Study
Authors' conclusion
Transgender adolescents starting testosterone, particularly those taking progestin, should be monitored for acne development and treated proactively by hormone providers and dermatologists.
Study context
- Population
- Patients aged <18 years, assigned female at birth, seen at Children's Healthcare of Atlanta Pediatric Endocrinology clinic for testosterone initiation, 2016–2019, with ≥1-year follow-up46 without baseline acne
- Participants
- 60 patients
- Exposure
- Progestin users vs nonusers
- Outcome
- Incidence of acne
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Incidence of acne after testosterone initiation
No baseline acne
46
77%
Developed acne within 1 year, among those without baseline acne
25
54%
Overall incidence proportion at 2 years
70%
Observational data: associations, not effects.
Further findings
Acne development by progestin use · more likely to develop acne with progestin · bivariable analysis
P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Incidence and Factors Associated With Acne in Transgender Adolescents on Testosterone: A Retrospective Cohort Study. Endocr Pract. Published 6 March 2023. doi:10.
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