Improvement of Glycemia Risk Index and Continuous Glucose Monitoring Metrics During Ramadan Fasting in Type 1 Diabetes: A Real-World Observational Study
Authors' conclusion
Ramadan fasting significantly improved GRI and its components in individuals with T1D. Incorporating GRI as a novel metric alongside classical CGM metrics could enhance glycemic control, highlighting the need for personalized diabetes management strategies.
Study context
- Population
- Individuals with T1D using intermittent scanning CGM (isCGM) who fasted during Ramadan
- Participants
- 186 individuals
- Exposure
- During Ramadan vs before and after Ramadan
- Outcome
- GRI and its components for hypoglycemia (CHypo) and hyperglycemia (CHyper)
Methodological detailsreal-world
- Real-world
Main finding
As reported in the abstract
GRI · during Ramadan
Before Ramadan
56.4
During Ramadan
25.6
- Glycemia risk index (GRI) improved during Ramadan
- 54.6%
Observational data: associations, not effects.
Further findings
| Outcome | Before Ramadan | During Ramadan |
|---|---|---|
| CHypo · during Ramadan | 6 | 2.4 |
| CHyper · during Ramadan | 21 | 12.5 |
- Components for hypoglycemia (CHypo) — CHypo decreased
- 60%
- CHyper — CHyper dropped
- 40.5%
Glycemic measures after Ramadan
- Benefits temporary; glycemic measures increased after Ramadan, returning to pre-Ramadan patterns
Subgroups
- Adolescents and patients on insulin pumps had more favorable outcomes
Correlation of GRI with other continuous glucose monitoring (CGM) metrics
- GRI and its components significantly correlated with other CGM metrics, maintained during and after Ramadan
Safety
Admissions for diabetes emergencies during Ramadan
- Participants admitted for diabetes emergencies
- 0
Original publication
Improvement of Glycemia Risk Index and Continuous Glucose Monitoring Metrics During Ramadan Fasting in Type 1 Diabetes: A Real-World Observational Study. J Diabetes Sci Technol. Published 29 November 2024. doi:10.
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