Type 2 & other diabetes

Improved treatment satisfaction with once-weekly insulin icodec compared with once-daily basal insulin in individuals with type 2 diabetes: An analysis of patient-reported outcomes and participant interviews from ONWARDS 2 and 5 and a physician survey from ONWARDS 1

Diabetes Res Clin PractPublished Secondary analysis of the ONWARDS 1, 2 and 5 randomised trials

Authors' conclusion

These results demonstrate improved treatment satisfaction with, and strong preferences for, once-weekly versus once-daily basal insulin. Treatment convenience and willingness to continue and recommend once-weekly basal insulin treatment were highlighted.

Study context

Population
Participants with T2D from ONWARDS 5 and 2, and physicians from ONWARDS 1
Comparison
Once-weekly insulin icodec vs once-daily basal insulin
Methodological detailsphase 3a, patient-reported outcomes, participant interviews, physician online survey
  • Phase 3a
  • Patient-reported outcomes
  • Participant interviews
  • Physician online survey

Primary result

As reported in the abstract

Total treatment satisfaction, change from baseline to end of treatment (ONWARDS 5 and 2)
  • Statistically significantly greater increase in total treatment satisfaction with icodec/icodec with app vs once-daily comparators, mostly driven by willingness to continue and recommend treatment

Further findings

Preference for once-weekly over once-daily basal insulin among icodec users (ONWARDS 2) · mainly owing to less frequent injections and ease of use — Icodec
93.7 %

Physician satisfaction and recommendation (ONWARDS 1)

Physicians reported greater satisfaction with once-weekly than once-daily basal insulin and were more likely to recommend once-weekly injections

Original publication

Improved treatment satisfaction with once-weekly insulin icodec compared with once-daily basal insulin in individuals with type 2 diabetes: An analysis of patient-reported outcomes and participant interviews from ONWARDS 2 and 5 and a physician survey from ONWARDS 1. Diabetes Res Clin Pract. Published 4 October 2024. doi:10.1016/j.diabres.2024.111885

Composed by AI from the published abstract and checked against it. How Briefs are made →

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