Improved treatment satisfaction with once-weekly insulin icodec compared with once-daily basal insulin in individuals with type 2 diabetes: An analysis of patient-reported outcomes and participant interviews from ONWARDS 2 and 5 and a physician survey from ONWARDS 1
Authors' conclusion
These results demonstrate improved treatment satisfaction with, and strong preferences for, once-weekly versus once-daily basal insulin. Treatment convenience and willingness to continue and recommend once-weekly basal insulin treatment were highlighted.
Study context
- Population
- Participants with T2D from ONWARDS 5 and 2, and physicians from ONWARDS 1
- Comparison
- Once-weekly insulin icodec vs once-daily basal insulin
Methodological detailsphase 3a, patient-reported outcomes, participant interviews, physician online survey
- Phase 3a
- Patient-reported outcomes
- Participant interviews
- Physician online survey
Primary result
As reported in the abstract
Total treatment satisfaction, change from baseline to end of treatment (ONWARDS 5 and 2)
- Statistically significantly greater increase in total treatment satisfaction with icodec/icodec with app vs once-daily comparators, mostly driven by willingness to continue and recommend treatment
Further findings
- Preference for once-weekly over once-daily basal insulin among icodec users (ONWARDS 2) · mainly owing to less frequent injections and ease of use — Icodec
- 93.7 %
Physician satisfaction and recommendation (ONWARDS 1)
- Physicians reported greater satisfaction with once-weekly than once-daily basal insulin and were more likely to recommend once-weekly injections
Original publication
Improved treatment satisfaction with once-weekly insulin icodec compared with once-daily basal insulin in individuals with type 2 diabetes: An analysis of patient-reported outcomes and participant interviews from ONWARDS 2 and 5 and a physician survey from ONWARDS 1. Diabetes Res Clin Pract. Published 4 October 2024. doi:10. 1016/ j. diabres. 2024. 111885
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