Type 2 & other diabetes

Impact of telemedical management on hospitalization and mortality in heart failure patients with diabetes: a post-hoc subgroup analysis of the TIM-HF2 trial

Cardiovasc DiabetolPublished Post-hoc subgroup analysis of the TIM-HF2 randomised trial

Primary result · Percentage of days lost due to cardiovascular hospitalization or deathResult — go to the resultHazard ratio 0.66 95% CI 0.48–0.90

Authors' conclusion

These results support the use of RPM in HF patients with diabetes.

Study context

Population
Heart failure (HF) patients with diabetes in NYHA class II/III with an HF-related hospital admission within the previous 12 months, irrespective of LVEF; Germany, August 2013–May 2018HF patients with diabetes
Participants
707 patients
Comparison
Usual care with added remote patient management vs usual care
Primary endpoint
Days lost due to unplanned cardiovascular hospitalization or due to death of any cause
Follow-up
1 year
Methodological detailsrandomized, controlled, unmasked (concealed randomization), multicentre
  • Randomized
  • Controlled
  • Unmasked (concealed randomization)
  • Multicentre

Primary result

As reported in the abstract

Percentage of days lost due to cardiovascular hospitalization or death

Hazard ratio

0.66

95% CI 0.48–0.90

RPMvs Usual care
HR 0.66 (95% CI 0.48–0.90)

Further findings

OutcomeHR (95% CI)
All-cause mortality0.52 (0.32–0.85)
OutcomeMean difference (95% CI)
Quality of life: change in MLHFQ global scoreImprovement in quality of life with RPM- 3.4 (- 6.2 to - 0.6)

Original publication

Impact of telemedical management on hospitalization and mortality in heart failure patients with diabetes: a post-hoc subgroup analysis of the TIM-HF2 trial. Cardiovasc Diabetol. Published 12 June 2024. doi:10.1186/s12933-024-02285-0

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