Impact of short-term application of continuous glucose monitoring system(Continuous Glucose Monitoring System (CGMS)) on long-term glycemic profile in adolescents and adults with type 1 diabetes mellitus: An open-label randomized control cross over study
Authors' conclusion
Intermittent application of CGMS for 2 weeks improves short- and long-term blood glucose control in T1D.
Study context
- Population
- Adolescents and adults with T1Drandomized 1:1:2
- Participants
- 68 adolescents
- Comparison
- Short-term rtCGM and isCGM vs SMBG only
- Primary endpoint
- Change in HbA1c
- Follow-up
- 3 months
Methodological detailsopen-label, crossover
- Open-label
- Crossover
Primary result
As reported in the abstract
HbA1c · 3 and 6 months
- HbA1c decreased significantly in Groups A and B at 6 months vs baseline, but not in Group C
- Group A vs Group C: HbA1c significantly lower in Group A at 3 and 6 months
Further findings
Fructosamine
- Fructosamine significantly decreased in Group B before and after cross-over
Glycemic variability indices
- Glycemic variability indices improved significantly after cross-over from isCGM to rtCGM
Original publication
Impact of short-term application of continuous glucose monitoring system(CGMS) on long-term glycemic profile in adolescents and adults with type 1 diabetes mellitus: An open-label randomized control cross over study. Diabetes Res Clin Pract. Published 12 March 2024. doi:10.
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