Impact of Simplification Strategies on Postmeal Glucose Excursions in Older Adults with Type 1 Diabetes and Hypoglycemia

Diabetes Technol TherPublished Post-hoc analysis of a randomised trial

Authors' conclusion

Simplification strategies in older adults with T1D resulted in fewer episodes of postmeal hypoglycemia without worsening episodes of postmeal hyperglycemia.

Study context

Population
Older adults with T1D (71 ± 5 years) and hypoglycaemia
Participants
88 adults
Comparison
Mealtime simplification strategies vs control
  • Interventionn = 47
  • Controln = 41reference
Primary endpoint
Weekly postmeal hypoglycemia and hyperglycemia episodes
Follow-up
Baseline to 6 months

Primary result

As reported in the abstract

Mean change in episodes of postmeal hypoglycemia
  • Intervention vs Control: P = 0.02
  • Intervention vs Control: P = 0.05
  • Intervention vs Control: P = 0.04

Further findings

OutcomeInterventionControlP value
Mean change in episodes of postmeal hyperglycemia · baseline to 6 monthsAfter breakfast−2.05−1P = 0.04
Mean change in episodes of postmeal hyperglycemia · baseline to 6 monthsAfter lunch−1.23−0.87P = 0.09
Mean change in episodes of postmeal hyperglycemia · baseline to 6 monthsAfter dinner−1.45−1.66P = 0.33

Baseline postmeal hypo- and hyperglycemia episodes

Similar number of episodes in intervention and control

Original publication

Impact of Simplification Strategies on Postmeal Glucose Excursions in Older Adults with Type 1 Diabetes and Hypoglycemia. Diabetes Technol Ther. Published 25 September 2025. doi:10.1177/15209156251370985

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