Impact of COVID-19 on clinical characteristics in type 2 diabetes patients: A prospective, longitudinal, observational study
Authors' conclusion
This study demonstrates a significant association between COVID-19, poor glycemic control, and clinical characteristics in type 2 diabetes patients over an extended period, highlighting the need for ongoing monitoring and management in this vulnerable population.
Study context
- Population
- Patients with pre-existing T2D, outpatient endocrinology departments of tertiary and secondary care hospitals, Islamabad, Pakistan, November 2022–April 2024420 analysed
- Participants
- 604 patients
- Exposure
- COVID-19-positive T2D patients vs controls
- Outcome
- Random blood glucose
- Follow-up
- Last visit (nine months)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Case
180.5
± 51.4
Control
160.8
± 51.5
P = 0.035
Observational data: associations, not effects.
Further findings
Baseline HbA1c, random blood glucose and haematological parameters
- Case group had significantly higher HbA1c and random blood glucose, and lower WBC, RBC, haemoglobin and platelet counts vs control
- P < 0.001
Haematological parameters · last follow-up visit
- Improvement in haematological parameters in both groups
Original publication
Impact of COVID-19 on clinical characteristics in type 2 diabetes patients: A prospective, longitudinal, observational study. Diabetes Res Clin Pract. Published 3 June 2025. doi:10. 1016/ j. diabres. 2025. 112316
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