Type 2 & other diabetes

Impact of COVID-19 on clinical characteristics in type 2 diabetes patients: A prospective, longitudinal, observational study

Diabetes Res Clin PractPublished Prospective longitudinal observational study

Authors' conclusion

This study demonstrates a significant association between COVID-19, poor glycemic control, and clinical characteristics in type 2 diabetes patients over an extended period, highlighting the need for ongoing monitoring and management in this vulnerable population.

Study context

Population
Patients with pre-existing T2D, outpatient endocrinology departments of tertiary and secondary care hospitals, Islamabad, Pakistan, November 2022–April 2024420 analysed
Participants
604 patients
Exposure
COVID-19-positive T2D patients vs controls
Outcome
Random blood glucose
Follow-up
Last visit (nine months)
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Case

180.5

± 51.4

Control

160.8

± 51.5

P = 0.035

Observational data: associations, not effects.

Further findings

Baseline HbA1c, random blood glucose and haematological parameters

Case group had significantly higher HbA1c and random blood glucose, and lower WBC, RBC, haemoglobin and platelet counts vs control
P < 0.001

Haematological parameters · last follow-up visit

Improvement in haematological parameters in both groups

Original publication

Impact of COVID-19 on clinical characteristics in type 2 diabetes patients: A prospective, longitudinal, observational study. Diabetes Res Clin Pract. Published 3 June 2025. doi:10.1016/j.diabres.2025.112316

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