The impact of hypothetical early life interventions on rapid weight gain during infancy and body mass index at 5 and 8 years in Norway: The Norwegian Mother, Father, and Child Cohort Study (MoBa)
Authors' conclusion
Our results suggested joint interventions on early life factors may reduce childhood BMI-for-age z-scores.
Study context
- Population
- Children in the Norwegian Mother, Father, and Child Cohort Study (MoBa) aged 2, 5 and 8 yearsChild Cohort Study (MoBa) aged 2 48,109 · 5 18,810 · 8 10,830
- Exposure
- Hypothetical interventions on early life factors and child energy balance-related behaviours (EBRB)
- Outcome
- Rapid weight gain during infancy (at 2 years); BMI-for-age z-score at 5 and 8 years
- Follow-up
- 2, 5 and 8 years
Methodological detailspopulation-based, parametric g-formula, hypothetical interventions, Early life interventions: maternal smoking during pregnancy, maternal weight before and during pregnancy, exclusive/partial breastfeeding for 6 months, complementary food introduced at 6 months, Child EBRB interventions for 5-y outcome (assessed at 3 y): screen time, fruit and vegetable intake, sugar-sweetened soft drink intake, Child EBRB interventions for 8-y outcome (assessed at 5 y): screen time, TV in bedroom, sleep hours, breakfast intake
- Population-based
- Parametric g-formula
- Hypothetical interventions
- Early life interventions: maternal smoking during pregnancy, maternal weight before and during pregnancy, exclusive/partial breastfeeding for 6 months, complementary food introduced at 6 months
- Child EBRB interventions for 5-y outcome (assessed at 3 y): screen time, fruit and vegetable intake, sugar-sweetened soft drink intake
- Child EBRB interventions for 8-y outcome (assessed at 5 y): screen time, TV in bedroom, sleep hours, breakfast intake
Main finding
As reported in the abstract
Average population-level difference under hypothetical interventions
- Rapid weight gain at 2 y, prenatal factors intervention
- −0.012 (−0.017, −0.007) (95% CI)
- Rapid weight gain at 2 y, early postnatal factors intervention
- −0.009 (−0.012, −0.005) (95% CI)
- Rapid weight gain at 2 y, prenatal and early postnatal factors combined
- −0.020 (−0.025, −0.015) (95% CI)
- Body mass index (BMI)-for-age z-score at 5 y, early life factors intervention
- −0.225 (−0.244, −0.207) (95% CI)
- BMI-for-age z-score at 5 y, child EBRB intervention
- 0.02 (−0.021, 0.024) (95% CI)
- BMI-for-age z-score at 5 y, early life factors and EBRB combined
- −0.223 (−0.249, −0.196) (95% CI)
- BMI-for-age z-score at 8 y, early life factors intervention
- −0.265 (−0.295, −0.236) (95% CI)
- BMI-for-age z-score at 8 y, child EBRB intervention
- −0.020 (−0.029, −0.011) (95% CI)
- BMI-for-age z-score at 8 y, early life factors and EBRB combined
- −0.285 (−0.315, −0.256) (95% CI)
Observational data: associations, not effects.
Original publication
The impact of hypothetical early life interventions on rapid weight gain during infancy and body mass index at 5 and 8 years in Norway: The Norwegian Mother, Father, and Child Cohort Study (MoBa). Pediatr Obes. Published 16 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →