Five-year follow-up of a randomized weight loss trial on a digital health behaviour change support system
Authors' conclusion
The 12-month HBCSS intervention was not able to maintain reduced weight better than non-HBCSS at 5 years. However, there were significant weight difference favouring HBCSS over the whole 5-year period. The decrease in the need for antihypertensives suggests that the significant weight loss by HBCSS at early years has a health-promoting legacy effect.
Study context
- Population
- Adults with overweight or obesity (BMI 27–35 kg m-2); randomised to cognitive behavioural therapy (CBT)-based group counselling, self-help guidance (SHG) or usual care, each with or without health behaviour change support system (HBCSS)
- Participants
- 532 adults
- Comparison
- Web-based HBCSS vs no HBCSS
- Primary endpoint
- Weight change (%) from baseline
- Follow-up
- Five years
Methodological detailsfive-year follow-up, 3×2 design: three intervention intensities, each divided into HBCSS and non-HBCSS
- Five-year follow-up
- 3×2 design: three intervention intensities, each divided into HBCSS and non-HBCSS
Primary result
As reported in the abstract
Mean weight change (%) from baseline
| Group | Value | p vs baseline |
|---|---|---|
| HBCSS | mean 1.5 (95% CI −0.02–2.9) % | p = 0.056 |
| non-HBCSS | mean 1.9 (95% CI 0.3–3.3) % | p = 0.005 |
Value
HBCSSmean 1.5 (95% CI −0.02–2.9) %
non-HBCSSmean 1.9 (95% CI 0.3–3.3) %
p vs baseline
HBCSSp = 0.056
non-HBCSSp = 0.005
Further findings
| Outcome | P value |
|---|---|
| Blood pressure medications started · over five-year periodFewer started with HBCSS | P = 0.046 |
Weight change (%) from baseline, SHG without HBCSS · five years
- SHG without HBCSS: statistically significant weight increase from baseline (95% CI 0.6 to 5.6, p = 0.010); other groups no significant increase
- 3.1
Original publication
Five-year follow-up of a randomized weight loss trial on a digital health behaviour change support system. Int J Obes (Lond). Published 15 March 2025. doi:10.
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