Ideal Cardiovascular Health and Adipokine Levels: The Multi-Ethnic Study of Atherosclerosis
Authors' conclusion
In a multi-ethnic cohort free of cardiovascular disease at baseline, individuals with average and optimal CVH scores had a more favorable adipokine profile than those with inadequate CVH scores.
Study context
- Population
- Multi-Ethnic Study of Atherosclerosis participants free of CVD with 7 cardiovascular health (CVH) metrics at baseline and serum adipokines measured a median of 2.4 years later; mean age 62.1 ± 9.8 years, 50.2% men
- Participants
- 1,842 participants
- Exposure
- Ideal CVH score categories
- Outcome
- Log-transformed adipokine levels (adiponectin, leptin, resistin) by CVH score
- Follow-up
- Median of 2.4 years later
Methodological detailsmulti-ethnic, multivariable linear regression, adjusted for sociodemographic factors
- Multi-ethnic
- Multivariable linear regression
- Adjusted for sociodemographic factors
Main finding
As reported in the abstract
Adipokine levels per 1-unit higher CVH score
- Adiponectin, per 1-unit higher CVH score
- 4% higher
- Leptin, per 1-unit higher CVH score
- 15% lower
- Resistin, per 1-unit higher CVH score
- 1% lower
- Optimal vs inadequate CVH: adiponectin
- 27% higher
- Optimal vs inadequate CVH: leptin
- 56% lower
Observational data: associations, not effects.
Original publication
Ideal Cardiovascular Health and Adipokine Levels: The Multi-Ethnic Study of Atherosclerosis. Endocr Pract. Published 5 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →