Hypothyroidism Prevalence in Children Aged 0 to 17 Years in the United States: A Real-World Study Using 2 National Claims Databases, 2013-2022
Authors' conclusion
Distinct age- and sex-dependent trends in pediatric hypothyroidism prevalence were observed over time. A substantial subpopulation of patients did not receive treatment despite known developmental risks.
Study context
- Population
- Children aged 0 to 17 years with hypothyroidism in the US, 2 large claims databases, 2013–2022
- Participants
- 7,214,633 children
- Outcome
- Annual prevalence of hypothyroidism and treated hypothyroidism
- Follow-up
- 2013 to 2022
Methodological details2 national US claims databases, pooled dataset
- 2 national US claims databases
- Pooled dataset
Main finding
As reported in the abstract
Hypothyroidism prevalence (per 1000 children)
Overall prevalence per 1000 children, 2022
3.49
Prevalence change 2013–2022, children <1 year (0.62 to 0.88)
43%
Prevalence change 2013–2022, children aged 1 to 3 years (0.70 to 0.94)
33%
Prevalence decrease 2013–2022, children aged 4-17 years
9% to 18%
Observational data: associations, not effects.
Further findings
Receipt of thyroid replacement therapy · 2022
- Females significantly more likely than males to receive treatment; largest difference at age 8 to 11 years (female vs male)
- 70.1% vs 61.5%
- Approximately two-thirds of children with hypothyroidism received thyroid replacement therapy
Original publication
Hypothyroidism Prevalence in Children Aged 0 to 17 Years in the United States: A Real-World Study Using 2 National Claims Databases, 2013-2022. Endocr Pract. Published 8 August 2026. doi:10.
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