Gender differences in hypoglycaemia in type 1 and insulin-treated type 2 diabetes: the Hypo-METRICS study
Authors' conclusion
Despite similar exposures to hypoglycaemia, there were differences in hypoglycaemia symptoms between genders in this free-living environment.
Study context
- Population
- People with T1D or insulin-treated T2D in a free-living environment (Hypo-METRICS study); T1D cohort 54% women, 76% routine continuous glucose monitor (CGM) users; T2D cohort 63% men, 41% routine CGM users274 T1D, 321 T2D
- Exposure
- Women vs men
- Outcome
- Symptomatic hypoglycaemia episodes per week
Methodological details10-week, free-living environment, blinded CGM
- 10-week
- Free-living environment
- Blinded CGM
Main finding
As reported in the abstract
- No significant differences in time in hypoglycaemia between genders in either cohort
- all p>0.05
Observational data: associations, not effects.
Further findings
Confusion as the only reported hypoglycaemia symptom, T1D cohort
| Outcome | Women | Men |
|---|---|---|
| Confusion alone, T2D cohort | — not stated in the abstract | 0.3% of symptomatic episodes |
— not stated in the abstract
Time in hypoglycaemia
- No significant differences in time in hypoglycaemia between genders in either cohort
- all p>0.05
Confusion alone, T2D cohort
- Confusion alone was not observed in women
Symptom combinations, T1D cohort
- Women reported a broader range of symptom combinations, spanning autonomic and neuroglycopenic symptoms
Symptom combinations, T2D cohort
- More symptom combinations; both genders reported a combination of autonomic and neuroglycopenic symptoms
Original publication
Gender differences in hypoglycaemia in type 1 and insulin-treated type 2 diabetes: the Hypo-METRICS study. Diabetologia. Published 20 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →