In-Hospital Diabetes Management by a Diabetes Team and Insulin Titration Algorithms Based on Continuous Glucose Monitoring or Point-of-Care Glucose Testing in Patients With Type 2 Diabetes (DIATEC): A Randomized Controlled Trial
Authors' conclusion
In-hospital CGM increased TIR by 15 percentage points, mainly by reducing TAR. CGM also lowered TBR, glycemic variability, prolonged hypoglycemic events, insulin usage, and in-hospital complications.
Study context
- Population
- Non-ICU hospitalized patients with T2D, 2 centres
- Participants
- 166 participants
- Comparison
- Continuous glucose monitoring (CGM)-guided vs POC glucose testing-guided insulin titration by diabetes teams
- Primary endpoint
- Difference in time in range (TIR) (3.9-10.0 mmol/L) between arms
- Follow-up
- During hospitalization
Methodological detailstwo-center
- Two-center
Primary result
As reported in the abstract
TIR (3.9-10.0 mmol/L)
P < 0.001
Further findings
TAR >10.0 mmol/L · lower with CGM
P = 0.001
CV · lower with CGM
P = 0.024
| Outcome | Relative difference (95% CI) | P value | |
|---|---|---|---|
| TBR <3.9 mmol/L | 0.57 (0.34–0.97) | P = 0.042 | |
| −0.500.51Difference (linear scale) |
| Outcome | IRR (95% CI) | P value | |
|---|---|---|---|
| Prolonged hypoglycemic events | 0.13 (0.04–0.46) | P = 0.001 | |
| 0.050.21520Incidence rate ratio (log scale) |
Total insulin dose · lower with CGM
P = 0.049
Safety
| Outcome | IRR (95% CI) | P value | |
|---|---|---|---|
| Composite of complications | 0.76 (0.59–0.98) | P = 0.032 | |
| 0.512Incidence rate ratio (log scale) |
Original publication
In-Hospital Diabetes Management by a Diabetes Team and Insulin Titration Algorithms Based on Continuous Glucose Monitoring or Point-of-Care Glucose Testing in Patients With Type 2 Diabetes (DIATEC): A Randomized Controlled Trial. Diabetes Care. Published 31 January 2025. doi:10.
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