Home monitoring of haemoglobin A1c in diabetes: A systematic review and narrative synthesis on accuracy, reliability and patient acceptability
Authors' conclusion
Microtubes/capillary tubes look promising as a method of self-collecting and posting capillary blood samples for the measurement of HbA1c based on the accuracy and reliability findings presented. DBS samples demonstrated comparatively poorer accuracy. Data on acceptability were limited and further research is needed.
Study context
- Population
- Adult studies comparing capillary to venous blood for measuring HbA1c, methods suitable for postage30 articles
- Comparison
- Self-collected capillary blood vs venous blood for HbA1c
- Outcome
- Agreement between capillary and venous HbA1c (MD and limits of agreement)
Pooled result
As reported in the abstract
| Group | MD range | Limits of agreement (LoA) width |
|---|---|---|
| Micro/cap | −0.4 to 1.4 | 2.4 to 6 |
| capDBS | −4.3 to 7.2 | 11.7 to 16.8 |
MD range
Micro/cap−0.4 to 1.4
capDBS−4.3 to 7.2
Limits of agreement (LoA) width
Micro/cap2.4 to 6
capDBS11.7 to 16.8
Further pooled results
Acceptability of self-collection kits
- Reported satisfaction
- 83%-96%
- Found it easy
- 87%-99%
- Would use it again
- 69%-94%
Original publication
Home monitoring of haemoglobin A1c in diabetes: A systematic review and narrative synthesis on accuracy, reliability and patient acceptability. Diabet Med. Published 17 January 2023. doi:10. 1111/ dme. 15033
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