Health Care Utilization and Costs Associated With Empagliflozin in Older Adults With Type 2 Diabetes
Authors' conclusion
Among older adults with diabetes, empagliflozin was associated with a lower number of inpatient days, hospitalizations, ED visits, and office visits and with lower costs of care compared with DPP-4is, especially in those with history of CVD.
Study context
- Population
- US Medicare fee-for-service beneficiaries aged ≥65 years with diabetes initiating empagliflozin or DPP-4is (August 2014 to September 2018); mean age 72 years, 51% with baseline cardiovascular disease (CVD)23,335 matched pairs
- Exposure
- Empagliflozin vs DPP-4i initiation
- Outcome
- Health care resource utilization (HCRU) and per-member per-year (PMPY) costs for inpatient and outpatient services and dispensed medications
Methodological details1:1 propensity score matched, Medicare fee-for-service claims
- 1:1 propensity score matched
- Medicare fee-for-service claims
Main finding
As reported in the abstract
HCRU and costs
Empagliflozin vs DPP-4isEstimate (95% CI)
HCRU and costs
RR, number of inpatient days 0.89(0.82–0.97)
HCRU and costs
RR, number of ED visits 0.86(0.82–0.91)
HCRU and costs
RR, number of hospitalizations 0.86(0.79–0.93)
HCRU and costs
RR, number of office visits 0.96(0.95–0.98)
- Health care resource utilization (HCRU) and costs
- Inpatient cost difference -$713 per-member per-year (PMPY) (95% CI −847 to −579)
- HCRU and costs
- Outpatient cost difference -$198 PMPY (95% CI −272 to −124)
- HCRU and costs
- Total cost of care difference -$1,109 PMPY (95% CI −1,478 to −739)
- Higher with empagliflozin
- Diabetes medication cost difference $454 PMPY (95% CI 284–567)
Observational data: associations, not effects.
Further findings
| Outcome | Total cost difference (PMPY) (CI) |
|---|---|
| Total cost, CVD subgroup | -$2,005 (−2,451 to −1,337) |
| Total cost, non-CVD subgroupDifference attenuated | -$296 (−740 to 148) |
Original publication
Health Care Utilization and Costs Associated With Empagliflozin in Older Adults With Type 2 Diabetes. Diabetes Care. Published 25 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →