Thyroid disease

Head-to-head comparison of American, European, and Asian TIRADSs in thyroid nodule assessment: systematic review and meta-analysis

Eur Thyroid JPublished Systematic review and meta-analysis

Authors' conclusion

ACR-, EU-, and K-TIRADS assess TNs similarly across their categories, with slight differences in low-risk classifications. Despite this, focusing on cancer risk estimation, the three TIRADSs assess TNs differently. These findings should be considered as a prerequisite for developing the I-TIRADS.

Study context

Population
Original studies that sequentially assessed thyroid nodules using TIRADSs, regardless of FNAC indication; PubMed and Embase searched until June 2023
Participants
41,332 participants7 studies
Comparison
ACR- vs EU- vs K-TIRADS
Outcome
Distribution of thyroid nodules across TIRADS categories and by estimated cancer risk
Methodological detailshead-to-head comparison
  • Head-to-head comparison

Pooled result

As reported in the abstract

Distribution of TNs across TIRADS categories
  • Prevalence of ACR-TIRADS 1-2 significantly higher than EU-TIRADS 2 and K-TIRADS 2
  • No significant difference among intermediate- and high-risk categories of TIRADSs
  • By malignancy risk estimation: K-TIRADS often classified thyroid nodules (TNs) as more severe risk, ACR-TIRADS as moderate risk, EU-TIRADS as lower risk

Original publication

Head-to-head comparison of American, European, and Asian TIRADSs in thyroid nodule assessment: systematic review and meta-analysis. Eur Thyroid J. Published 15 March 2024. doi:10.1530/etj-23-0242

Composed by AI from the published abstract and checked against it. How Briefs are made →

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