Glucose control during Ramadan in a pediatric cohort with type 1 diabetes on MiniMed standard and advanced hybrid closed‑loop systems: A pilot study
Authors' conclusion
Standard and advanced HCL use during Ramadan were safe and were associated with a maintained optimum TIR (>70 %) and no significant hypoglycemia in adolescents and older children with T1D.
Study context
- Population
- Children and adolescents aged 8–16 years with T1D on MiniMed standard hybrid closed-loop (HCL) (670G) or advanced HCL (780G); mean age 11.35 ± 2 years8 standard, 11 advanced HCL
- Participants
- 19 children
- Exposure
- Fasting vs nonfasting during Ramadan on HCL systems
- Fastingn = 11
- Outcome
- Efficacy and safety (glucose control outcomes) of HCL during Ramadan fasting
- Follow-up
- During Ramadan and 1 month before Ramadan
Main finding
As reported in the abstract
Insulin and glucose control metrics (CV, TIR, time in hypoglycemia) · during Ramadan
- No significant difference between fasting and nonfasting in insulin and glucose control metrics; practically the same CV, time in range (TIR) and time in hypoglycemia, within international recommended targets
- Pump setup and sensor statistics the same during Ramadan and the month before
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Total daily insulin dose · during Ramadan | P = 0.01 |
- Total daily insulin dose: higher with Fasting, without repercussions on glucose control metrics
Original publication
Glucose control during Ramadan in a pediatric cohort with type 1 diabetes on MiniMed standard and advanced hybrid closed‑loop systems: A pilot study. Diabetes Res Clin Pract. Published 4 August 2023. doi:10. 1016/ j. diabres. 2023. 110867
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