Type 2 & other diabetes

GLP-1 receptor agonist adjunct therapy stabilises Ramadan dysglycaemia in insulin-treated diabetes: a continuous glucose monitoring (CGM)-based study

Diabetes Res Clin PractPublished Retrospective cohort study

Main finding · CGM metrics during Ramadan, BB+ vs BBResult — go to the resultReduction in incremental post-iftar AUC ≈61 %

Authors' conclusion

In matched insulin-treated type 2 diabetes cohorts, add-on semaglutide or tirzepatide stabilised Ramadan glycaemia and reduced post-iftar hyperglycaemia without increasing hypoglycaemia, and was well tolerated with no treatment discontinuations during Ramadan.

Study context

Population
Adults with T1D or T2D using FreeStyle Libre CGM who completed ≥ 14 full fasting days during Ramadan 2025140 screened
Participants
54 adults
Exposure
Basal-bolus insulin plus tirzepatide or semaglutide vs basal-bolus insulin alone in insulin-treated T2D during Ramadan
  • BBn = 18reference
  • BB+n = 18
  • T1DMn = 18
Outcome
CGM metrics during Ramadan, BB+ vs BB
Follow-up
Ramadan (1-29 March 2025)
Methodological detailsCGM-based, matched 1:1 by age, baseline HbA1c and BMI
  • CGM-based
  • Matched 1:1 by age, baseline HbA1c and BMI

Main finding

As reported in the abstract

Reduction in incremental post-iftar AUC

≈61 %

By group

Observational data: associations, not effects.

Original publication

GLP-1 receptor agonist adjunct therapy stabilises Ramadan dysglycaemia in insulin-treated diabetes: a CGM-based study. Diabetes Res Clin Pract. Published 10 June 2026. doi:10.1016/j.diabres.2026.113369

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