Gestational diabetes & diabetes in pregnancy
Gestational diabetes mellitus in early pregnancy amongst Asian Indian women: Evidence for poor pregnancy outcomes despite treatment
Authors' conclusion
Asian Indian women having a GDM diagnosis before 24Gw are at higher risk for adverse pregnancy events than those having diagnosis ≥24Gw or not having GDM.
Study context
- Population
- Asian Indian pregnant women, singleton pregnancies, first-trimester HbA1c <48 mmols/mol (6.5%), GDM screening by 75 g OGTT (IADPSG criteria), delivery at the centre; January 2011–September 2017
- Participants
- 2,638 women
- Exposure
- Early GDM vs standard GDM vs no GDM
- Outcome
- Pregnancy outcomes by timing of GDM diagnosis
Methodological detailsmultivariable logistic regression
- Multivariable logistic regression
Main finding
As reported in the abstract
Pregnancy outcomes vs Non-GDM
- Early GDM (E-GDM) vs Non-GDM: higher odds of premature birth, large for gestational age (LGA) babies, macrosomia, Neonatal ICU (NICU) admission; lower odds of normal vaginal delivery
- Standard GDM (S-GDM) vs Non-GDM: higher risk of premature birth, LGA babies, NICU admission and induction of labour
Observational data: associations, not effects.
Further findings
Subgroup of GDM women by gestational age at diagnosis
- Increase in odds of premature birth per 4-week decrease in gestational age at GDM diagnosis
- 19%
- <14 gestational weeks (Gw) vs 24-28 Gw: significantly higher odds of premature birth and LGA babies
Original publication
Gestational diabetes mellitus in early pregnancy amongst Asian Indian women: Evidence for poor pregnancy outcomes despite treatment. Diabet Med. Published 17 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →