Diabetes technology

Fully Closed-Loop Insulin Delivery in Patients Undergoing Pancreatic Surgery

Diabetes Technol TherPublished Post hoc subgroup analysis of a randomised controlled trial

Primary result · % time in target range 5.6-10.0 mmol/LResult — go to the resultMean difference 36.6 % 95% CI 18.5–54.8

Authors' conclusion

Findings suggest that an adaptive SC FCL approach effectively accommodated the highly variable insulin needs in patients undergoing pancreatic surgery.

Study context

Population
Patients undergoing partial or total pancreatic resection
Comparison
Subcutaneous (SC) fully closed-loop vs usual care insulin therapy
Primary endpoint
% time with continuous glucose monitoring (CGM) values in target range 5.6–10.0 mmol/L
Follow-up
Over the time of hospitalization

Primary result

% time in target range 5.6-10.0 mmol/L

Mean difference

36.6 %

95% CI 18.5–54.8

By group

FCLvs UC
mean difference 36.6 % (95% CI 18.5–54.8)

As reported in the abstract

Safety

Fully closed-loop (FCL) did not increase the risk of hypoglycaemia

Original publication

Fully Closed-Loop Insulin Delivery in Patients Undergoing Pancreatic Surgery. Diabetes Technol Ther. Published 14 December 2022. doi:10.1089/dia.2022.0400

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