FRONTIER—FreeStyle Libre System Use in Ontario Among People with Diabetes Mellitus in the IC/ES Database—Evidence from Real-World Practice: Patients Using Intensive Insulin
Authors' conclusion
Among people with T1DM or T2DM on MDI, HbA1c was statistically significantly reduced after FSL, with statistically significant reductions in HCRU in some subgroups.
Study context
- Population
- People with diabetes on MDI with a first FSL claim between September 16, 2019, and August 31, 2020, who remained on FSL for 24 months; Ontario, Canada (IC/ES)
- Exposure
- HbA1c and health care resource utilization (HCRU) before vs after FSL adoption
- Outcome
- HbA1c and HCRU (ED visits and hospitalization) before and after FSL adoption
- Follow-up
- 12 months before index date vs last 12 months
Methodological detailsbefore-after comparison, administrative health data
- Before-after comparison
- Administrative health data
Main finding
As reported in the abstract
Change in mean HbA1c after FSL
- T1D (n = 10,510), age <25 years
- −0.8%
- T1D, age 25-65 years
- −0.5%
- T1D, age >65 years
- −0.1%
- T2D (n = 12,668), age ≤65 years
- −0.6%
- T2D, age >65 years
- −0.3%
Observational data: associations, not effects.
Further findings
- Overall HCRU statistically significantly reduced in T1D aged <25 and 25-65 years (ED visits only) and both T2D age subgroups; some subgroups had significant reductions in diabetic ketoacidosis (DKA)- or hypoglycemia-associated HCRU
Original publication
FRONTIER—FreeStyle Libre System Use in Ontario Among People with Diabetes Mellitus in the IC/ES Database—Evidence from Real-World Practice: Patients Using Intensive Insulin. Diabetes Technol Ther. Published 19 February 2025. doi:10.
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