Forearm bone mineral density (BMD) predicts fracture independently of FRAX
Authors' conclusion
Forearm BMD is a risk factor for MOF and hip fracture risk beyond the risk attributable to FRAX.
Study context
- Population
- Men and women from 11 predominantly population-based cohorts, mean follow-up 11.1 years
- Participants
- 35,121 men11 cohorts
- Comparison
- Forearm BMD per 1 SD difference, with and without adjustment for FRAX
- Outcome
- Gradient of risk (HR per 1 SD difference in forearm BMD) for major osteoporotic fracture
Methodological detailspredominantly population-based cohorts, Poisson regression extension, weighted coefficients
- Predominantly population-based cohorts
- Poisson regression extension
- Weighted coefficients
Pooled result
As reported in the abstract
Major osteoporotic fracture, GR of forearm BMD
Gradient of risk (GR) adjusted for age and time since baseline
1.41
95% CI 1.31–1.51
GR additionally adjusted for FRAX 10-year probability of MOF
1.34
95% CI 1.26–1.44
Further pooled results
Hip fracture, GR of forearm BMD
- GR
- 1.48 (95% CI 1.35-1.62)
- GR after adjustment for FRAX
- 1.39 (95% CI 1.27-1.52)
Original publication
Forearm BMD predicts fracture independently of FRAX. Osteoporos Int. Published 23 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →