Fifteen Years of Iodine Prophylaxis in Italy: Results of a Nationwide Surveillance (Period 2015-2019)
Authors' conclusion
Fifteen years of iodine prophylaxis have led to iodine sufficiency in Italy, although there still is concern about iodine nutritional status during pregnancy.
Study context
- Population
- Italian population after 2005 voluntary iodine prophylaxis program: adults, school canteens, schoolchildren aged 11–13 years, neonates screened in Northern, Central and Southern Italy
- Outcome
- Efficiency, effectiveness and adverse effects of iodine prophylaxis
- Follow-up
- 2015–2019
Methodological detailsnationwide survey, 2015–2019
- Nationwide survey
- 2015–2019
Main finding
As reported in the abstract
- Use of iodized salt, adults (n=164 593)
- 71.5%
- Use of iodized salt, school canteens (n=998)
- 78%
- Median urinary iodine concentration, schoolchildren (n=4233)
- 124 μg/L
- Prevalence of goiter, schoolchildren
- 2.2%
- Prevalence of thyroid hypoechogenicity on US, schoolchildren
- 5.7%
- Neonatal TSH values >5.0 mIU/L (n=197 677), still higher than WHO threshold of 3.0%
- 5.1%
- Reduction in MMI prescriptions
- 13.5%
Observational data: associations, not effects.
Original publication
Fifteen Years of Iodine Prophylaxis in Italy: Results of a Nationwide Surveillance (Period 2015-2019). J Clin Endocrinol Metab. Published 11 October 2023. doi:10.
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