Extracorporeal shock wave therapy (extracorporeal shockwave therapy (ESWT)) favors healing of diabetic foot ulcers: A systematic review and meta-analysis
Pooled result · Complete healed ulcersResult — go to the resultRelative risk 1.57 95 % CI 1.26–1.95Authors' conclusion
ESWT has shown promising efficacy and a favorable safety profile in the treatment of DFUs.
Study context
- Population
- Patients with diabetic foot ulcers (DFUs); Randomized controlled trials (RCTs) published before August 8, 202310 RCTs
- Comparison
- ESWT vs controls
- Outcome
- Complete healed ulcers
Pooled result
As reported in the abstract
Relative risk
1.57
95 % CI 1.26–1.95
ESWTvs Controls
RR 1.57 (95 % CI 1.26–1.95)
Further pooled results
| Outcome | RR (95 % CI) | |
|---|---|---|
| Unchanged ulcers | 0.25 (0.14–0.42) | |
| 0.10.31310Relative risk (log scale) |
| Outcome | MD (95 % CI) | P value | |
|---|---|---|---|
| Average TcPO2 | 1.71 (1.22–2.19) | P < 0.001 | |
| −10123Difference (linear scale) |
Subgroups by control: Hyperbaric oxygen therapy (HOT) and standard of care (SOC)
- ESWT was better than both HOT and SOC
≥ 50 % improved ulcers
- Not significantly different between ESWT and controls
Safety
- Treatment-emergent adverse events (TEAEs) not significantly different between ESWT and controls
Original publication
Extracorporeal shock wave therapy (ESWT) favors healing of diabetic foot ulcers: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 3 September 2024. doi:10. 1016/ j. diabres. 2024. 111843
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