Obesity

Exploring the link between dietary inflammatory index, inflammatory biomarkers, and sleep quality in adults with obesity: a pilot investigation

Int J Obes (Lond)Published Cross-sectional study

Authors' conclusion

These findings suggest that an anti-inflammatory diet can effectively reduce inflammation and BMI in people with obesity, but has a limited effect on sleep quality. Therefore, it is recommended that dietitians integrate anti-inflammatory dietary strategies for people with obesity into their clinical practice.

Study context

Population
Adults with obesity (F: 75; M: 49), mean age 42.20 ± 11.00 years, presenting to a dietary outpatient clinic in Malatya, November 2021–May 2022
Participants
124 adults
Exposure
Higher vs lower Dietary Inflammatory Index score
Outcome
Relationship of DII (3-day dietary records) with inflammatory biomarkers and sleep quality
Methodological detailspilot investigation
  • Pilot investigation

Main finding

As reported in the abstract

DII vs inflammatory biomarkers, BMI and sleep quality
C-reactive protein (CRP) significantly higher in groups with higher Dietary Inflammatory Index (DII) score
p = 0.006
Correlation of DII with CRP
r = 0.258; p = 0.004
Correlation of DII with total cholesterol
r = −0.243; p = 0.007
Body Mass Index (BMI) increased as dietary inflammatory burden increased
p = 0.009
No significant correlation between DII and sleep quality
p = 0.348

Observational data: associations, not effects.

Original publication

Exploring the link between dietary inflammatory index, inflammatory biomarkers, and sleep quality in adults with obesity: a pilot investigation. Int J Obes (Lond). Published 30 January 2025. doi:10.1038/s41366-025-01728-2

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