Obesity

Evidence for protein leverage on total energy intake, but not body mass index, in a large cohort of older adults

Int J Obes (Lond)Published Retrospective cohort study

Authors' conclusion

Findings indicate clear evidence for PL on TEI, but not on BMI, likely because of aging, body composition, sarcopenia, or protein wasting.

Study context

Population
Community-dwelling older adults aged 67–84 years from the NuAge cohort
Participants
1,699 adults
Outcome
Protein leverage: association of protein energy contribution with TEI (and BMI)
Methodological detailscommunity-dwelling older adults, NuAge cohort, mixture models, power functions
  • Community-dwelling older adults
  • NuAge cohort
  • Mixture models
  • Power functions

Main finding

As reported in the abstract

Protein leverage on TEI

Strength of leverage (L), protein energy contribution (EC) vs total energy intake (TEI) (strong negative association; p < 0.001)

−0.37

TEI reduction per percent of energy from protein, on average, ceteris paribus

77 kJ

Observational data: associations, not effects.

Further findings

Cohort description

Obesity
53%
Severe obesity
1.5%
Mean TEI
7673 kJ
EC from carbohydrates
50.4%
EC from fat
33.2%
EC from protein
16.4%

Original publication

Evidence for protein leverage on total energy intake, but not body mass index, in a large cohort of older adults. Int J Obes (Lond). Published 25 December 2023. doi:10.1038/s41366-023-01455-6

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