Endothelial microRNAs in ischemia with non-obstructive coronary artery (INOCA) patients with diabetes mellitus
Authors' conclusion
We detected a significant dysregulation of miR-363-5p and miR-92a-3p in INOCA patients with DM compared to those without DM, indicating their role as biomarkers for predicting and monitoring endothelial dysfunction in INOCA patients with DM.
Study context
- Population
- Consecutive INOCA patients undergoing percutaneous coronary intervention
- Exposure
- INOCA with diabetes mellitus (DM) vs without DM
- Outcome
- Expression of a panel of circulating microRNAs (miRNAs) regulating endothelial function (RT-qPCR)
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Circulating endothelial miRNA expression
- Significant dysregulation of miR-363-5p and miR-92a-3p in INOCA with DM vs without DM
Observational data: associations, not effects.
Original publication
Endothelial microRNAs in INOCA patients with diabetes mellitus. Cardiovasc Diabetol. Published 22 July 2024. doi:10.
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