Effects of Physical Activity on Blood Lipids and Hemoglobin A1c in Healthy Pregnant Women: The FitMum Randomized Controlled Trial
Authors' conclusion
Whilst there were no effects of offering PA interventions, higher PA was associated with reduced increases in TC, HDL-C, and LDL-C as pregnancy progressed.
Study context
- Population
- Healthy pregnant women included before week 15 + 0
- Participants
- 216 women
- Comparison
- Two physical activity (PA) interventions throughout pregnancy vs standard care
- Primary endpoint
- Maternal blood lipid (TC, HDL-C, LDL-C, TG) and HbA1c concentrations
- Follow-up
- Week ≤15 + 0, 28+0-6, 34+0-6, and at delivery
Primary result
As reported in the abstract
Maternal lipids and HbA1c · during pregnancy
- No effects of the PA interventions on maternal lipids or hemoglobin A1c (HbA1c)
- Linear mixed effects models
Further findings
PA per se (activity tracker): min/week of moderate-to-vigorous PA and increase in lipids as pregnancy progresses
- Less increase in total cholesterol (TC)
- −1.3E-04, P = .020
- Less increase in low-density lipoprotein cholesterol (LDL-C)
- −8.5E-05, P = .035
- Linear regression
PA per se (activity tracker): active kilocalories and increase in lipids as pregnancy progresses
- Less increase in TC
- −5.5E-05, P < .001
- Less increase in high-density lipoprotein cholesterol (HDL-C)
- −9.5E-06, P = .024
- Less increase in LDL-C
- −3.2E-05, P = .005
- Linear regression
Original publication
Effects of Physical Activity on Blood Lipids and Hemoglobin A1c in Healthy Pregnant Women: The FitMum Randomized Controlled Trial. Endocr Pract. Published 9 July 2024. doi:10. 1016/ j. eprac. 2024. 07. 002
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