Effects of energy loads on energy and nutrient absorption rates and gut microbiome in humans: A randomized crossover trial
Authors' conclusion
Although short-term overfeeding dynamically altered the gut microbiota composition, the energy excretion rate via feces was unaffected. Energy excretion rates via urine and urine plus feces were lower under OF than under CON and UF conditions.
Study context
- Population
- Healthy men; each condition for 8 days (4 days and 3 nights in nonlaboratory and laboratory settings each)
- Participants
- 10 men
- Comparison
- Overfeeding vs control vs underfeeding
- Primary endpoint
- Gut microbiota composition and rates of energy and nutrient excretion via feces and urine
Methodological detailsdietary intervention
- Dietary intervention
Primary result
As reported in the abstract
- Overfeeding (OF) vs control (CON)
- difference (urine) −0.7 %; P < 0.001
- OF vs CON
- difference (urine plus feces) −1.9 %; P = 0.049
- OF vs underfeeding (UF)
- difference (urine) −1.0 %; P < 0.001
- OF vs UF
- difference (urine plus feces) −2.1 %; P = 0.031
- Short-term energy loads altered gut microbiota at α-diversity (Shannon index), phylum and genus levels
- P < 0.05
Original publication
Effects of energy loads on energy and nutrient absorption rates and gut microbiome in humans: A randomized crossover trial. Obesity (Silver Spring). Published 5 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →