Effects of mindfulness-based interventions (MBIs) on psychological outcomes and HbA1C in patients with diabetes: A systematic review and meta-analysis of randomized controlled trials
Authors' conclusion
To sum up, mindfulness-based therapies markedly improved HbA1c levels and psychological outcomes, among individuals with diabetes mellitus.
Study context
- Population
- Individuals with DM; mean age ranged from 18.3 to 66.3 years
- Participants
- 1,987 individuals24 primary studies
- Comparison
- Mindfulness-based interventions vs control
- MBIsn = 942
- Controlsn = 955reference
- Outcome
- HbA1c and psychological outcomes
Methodological detailsrandom-effects model, subgroup analyses, Nine electronic databases searched from inception through May 2025
- Random-effects model
- Subgroup analyses
- Nine electronic databases searched from inception through May 2025
Pooled result
As reported in the abstract
Each group vs controlsHedges' g (HbA1c) (95% CI)P value
MBIs
0.564(0.221–0.908)
P = 0.001- MBIs
- g (stress) 1.132 (95% CI 0.551–1.714); P < 0.001
- MBIs
- g (anxiety) 1.321 (95% CI 0.569–2.072); P = 0.001
- MBIs
- g (depression) 1.059 (95% CI 0.564–1.555); P < 0.001
Further pooled results
- MBI format, ITT analysis, concealed allocation, attrition, funding sources and a priori analysis were modifiers affecting the effect size
Original publication
Effects of mindfulness-based interventions (MBIs) on psychological outcomes and HbA1C in patients with diabetes: A systematic review and meta-analysis of randomized controlled trials. Diabetes Res Clin Pract. Published 11 May 2026. doi:10.
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