Effect of diabetes mellitus on young female patients with acute coronary syndrome
Authors' conclusion
DM is an important risk factor in young females with ACS. Young women with diabetes are prone to coronary heart disease. The coronary artery lesions in DM patients were more severe than those in Non-DM patients, despite the protective effect of estrogen on the cardiovascular system. Therefore, young women with DM should be treated to prevent ACS and future events activelyandpurposefully.
Study context
- Population
- Young females (age ≤ 44 years) undergoing coronary angiography
- Participants
- 1,278 females
- Exposure
- Diabetes mellitus (DM) vs control in young females undergoing coronary angiography
- DMn = 197
- Controln = 1,081reference
- Outcome
- Prevalence of acute coronary syndrome (ACS)
Main finding
As reported in the abstract
P < 0.05
Observational data: associations, not effects.
Further findings
Overweight · significantly higher with DM
P < 0.05
Depression or anxiety · significantly higher with DM
P < 0.05
| Outcome | P value |
|---|---|
| All-cause death at follow-upDM-ACS vs Non-DM-ACS · significantly higher with DM-ACS | P < 0.05 |
- Type A lesions (DM-ACS vs Non-DM-ACS) · lower proportion with DM-ACS
- P < 0.05
- Type C lesions (DM-ACS vs Non-DM-ACS) · significantly higher with DM-ACS
- P < 0.01
- Number of stents implanted (DM-ACS vs Non-DM-ACS) · no significant difference
- P > 0.05
- Length of stent implantation (DM-ACS vs Non-DM-ACS) · significantly longer with DM-ACS
- P < 0.05
- MACE at follow-up (DM-ACS vs Non-DM-ACS) · not statistically significant
- P > 0.05
- All-cause death at follow-up: DM-ACS 2.98%
- All-cause death at follow-up: Non-DM-ACS 0.36%
Prevalence of diabetes
- Prevalence of diabetes
- 15.41% (197/1278)
Original publication
Effect of diabetes mellitus on young female patients with acute coronary syndrome. Diabetes Res Clin Pract. Published 12 September 2023. doi:10.
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