Effect of Conventional Treatment on Dental Complications and Ectopic Ossifications Among 30 Adults With X-linked Hypophosphatemia (XLH)
Authors' conclusion
Early treatment could prevent dental complications but did not prevent ectopic ossification in adult patients with XLH. The difference in the preventive effect was not observed among different types of teeth.
Study context
- Population
- Adults with XLH; orthopantomograms, spinal CT and X-rays of hip/knee joints studied
- Participants
- 30 adults
- Exposure
- Early vs late conventional treatment
- Outcome
- Dental complications
Main finding
As reported in the abstract
- Number of sound teeth significantly lower with late treatment
- Decayed, missing, filled (DMF) index significantly higher with late treatment
- Severity of dental complications in anterior and molar teeth not significantly different between early and late treatment
Observational data: associations, not effects.
Further findings
Ectopic ossification: spinal ligament ossification (OA/OP/OY/OS index) and hip/knee osteophytes (Kellgren-Lawrence (KL) grade)
- OA/OP/OY/OS index and KL grade not significantly different between early and late treatment
Original publication
Effect of Conventional Treatment on Dental Complications and Ectopic Ossifications Among 30 Adults With XLH. J Clin Endocrinol Metab. Published 16 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →