Economic burdens of type 1 diabetes and its complications: A nationwide, longitudinal analysis
Authors' conclusion
Our findings not only support the parameterization of diabetes economic models to determine cost-effective interventions for T1D but also highlight the importance of early prevention for T1D progression.
Study context
- Population
- T1D patients from Taiwan's National Health Insurance Research Database, 2008–2016, followed until death or 12/31/2018mean follow-up 9.1 years
- Participants
- 10,137 patients
- Outcome
- Healthcare costs by T1D-related complications and across time
Methodological detailsnationwide, longitudinal, generalized estimating equation model
- Nationwide
- Longitudinal
- Generalized estimating equation model
Main finding
As reported in the abstract
Cost increase by complication
- Event/occurrence years: from nephropathy to IHD/MI
- 1.13-fold to 1.79-fold
- State/subsequent years: from diabetic foot or neuropathy to peripheral vascular disease
- 1.02-fold to 1.71-fold
- Recurrent CV events, event-year: cerebrovascular disease to IHD/MI
- 1.19-fold to 1.84-fold
- Hospitalized hyperglycemia
- 1.26-fold
- Hospitalized hypoglycemia
- 1.36-fold
- Event-year: kidney transplant
- 5.96-fold
- Event-year: hemorrhagic stroke
- 1.77-fold
- State-year: kidney transplant
- 18.26-fold
- State-year: end-stage renal disease
- 3.40-fold
- CVD death
- 1.93-fold
- Other-cause death
- 1.64-fold
Observational data: associations, not effects.
Original publication
Economic burdens of type 1 diabetes and its complications: A nationwide, longitudinal analysis. Diabetes Res Clin Pract. Published 16 June 2025. doi:10.
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