European Association for the Study of Obesity (EASO) 's New Obesity Framework and Incident Type 2 Diabetes: A Prospective Cohort Study
Authors' conclusion
The new EASO framework may improve the identification of individuals at high risk of incident type 2 diabetes mellitus compared with traditional BMI criteria alone.
Study context
- Population
- Adults without diabetes at baseline, NAfld in the Gifu Area Longitudinal Analysis (NAGALA) community-based health screening cohort, Japan
- Participants
- 13,825 adults
- Exposure
- EASO-defined overweight and new obesity vs normal weight
- EASO-defined new obesityn = 1,424
- Outcome
- Incident T2D (haemoglobin A1c (HbA1c) ≥ 6.5%, FPG ≥ 7.0 mmol/L, or self-reported physician diagnosis)
Methodological detailscommunity-based
- Community-based
Main finding
As reported in the abstract
Incident T2D
Each group vs normal weightEstimate (95% CI)
EASO-defined overweight
HR 1.48(1.10–2.00)
EASO-defined new obesity
HR 5.06(3.86–6.62)
EASO-defined new obesityadjusted for age, sex, smoking, alcohol, physical activity, HbA1c
aHR 2.68(2.03–3.54)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Incident T2D vs normal weight without comorbiditiesEASO-defined new obesityvs Normal weight without comorbidities | 4.14 (2.77–6.19) | |
| Incident T2D vs normal weight without comorbiditiesNormal weight with comorbiditiesvs Normal weight without comorbidities | 1.95 (1.30–2.92) | |
| 0.10.31310Hazard ratio (log scale) |
Reclassified as obesity by EASO definition · baseline
- Reclassified as having obesity (31.3% of those overweight by body mass index (BMI))
- 10.3% (1424 individuals)
Original publication
EASO 's New Obesity Framework and Incident Type 2 Diabetes: A Prospective Cohort Study. Diabetes Obes Metab. Published 17 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →