Disordered Eating Behaviors Among Adolescents and Young Adults with Type 1 Diabetes Treated with Insulin Pumps and Hybrid Closed-Loop Systems
Authors' conclusion
DEB are common among individuals with T1D treated with insulin pumps and are associated with higher HbA1c levels. Among T1D individuals with DEB, HCL system use is associated with lower HbA1c compared to insulin pump treatment.
Study context
- Population
- Insulin pump-treated individuals with T1D, 13–21 years of age
- Participants
- 167 individuals
- Exposure
- Hybrid closed-loop (HCL) systems vs insulin pumps, by disordered eating behaviors (DEB) level
- Outcome
- DEB prevalence and risk factors
Methodological detailsobservational, Data from medical charts with additional self-reported questionnaires, including DEB assessment
- Observational
- Data from medical charts with additional self-reported questionnaires, including DEB assessment
Main finding
As reported in the abstract
- DEB found
- 71 (42.5%)
- DEB associated with female sex
- β = 2.98 [SE = 1.31], P = 0.025
- DEB associated with BMI-Z-score
- β = 2.12 [SE = 0.64], P = 0.001
- DEB associated with hemoglobin A1c (HbA1c)
- β = 1.40 [SE = 0.45], P = 0.02
- DEB associated with higher rate of pump discontinuation
- β = 4.48 [SE = 1.99], P = 0.026
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| HCL vs insulin pump use among individuals without DEBHCLvs Insulin pumpsHigher BMI-Z-score | 3.46 (1.52–7.87) | P = 0.003 | |
| HCL vs insulin pump use among individuals without DEBHCLvs Insulin pumpsTendency to lower HbA1c | 0.44 (0.18–1.09) | P = 0.078 | |
| HCL vs insulin pump use among individuals with DEBHCLvs Insulin pumpsLower HbA1c | 0.29 (0.10–0.83) | P = 0.022 | |
| HCL vs insulin pump use among individuals with DEBHCLvs Insulin pumpsHigher socioeconomic status | 1.73 (1.09–2.74) | P = 0.020 | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Disordered Eating Behaviors Among Adolescents and Young Adults with Type 1 Diabetes Treated with Insulin Pumps and Hybrid Closed-Loop Systems. Diabetes Technol Ther. Published 3 January 2024. doi:10.
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