Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas
Authors' conclusion
Our results did not show usefulness of the DWI and T1WI for assessing the consistency of pituitary macroadenomas, nor as a predictor of the degree of surgical resection.
Study context
- Population
- Patients with pituitary macroadenoma and surgical indication; pre-surgical magnetic resonance imaging (MRI) with T1-weighted imaging (T1WI) before and after contrast and diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) map
- Participants
- 80 patients
- Comparison
- Soft vs intermediate/hard macroadenomas
- Softn = 53
- Intermediate/hardn = 27reference
- Outcome
- Prediction of macroadenoma consistency at surgery by mean ADC, T1WI signal and tumor-to-pons ADC ratio (ADCR)
Performance
As reported in the abstract
ADC · pre-surgical
Further findings
Grade of surgical resection (tumor residue) · post-surgical MRI ≥3 months after surgery
- No significant difference in median ADC, ADCR and T1W signal between patients with and without tumor residue
Original publication
Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas. Pituitary. Published 25 January 2024. doi:10. 1007/ s11102-023-01377-6
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