Pituitary & hypothalamus

Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas

PituitaryPublished Prospective diagnostic accuracy study

Authors' conclusion

Our results did not show usefulness of the DWI and T1WI for assessing the consistency of pituitary macroadenomas, nor as a predictor of the degree of surgical resection.

Study context

Population
Patients with pituitary macroadenoma and surgical indication; pre-surgical magnetic resonance imaging (MRI) with T1-weighted imaging (T1WI) before and after contrast and diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) map
Participants
80 patients
Comparison
Soft vs intermediate/hard macroadenomas
  • Softn = 53
  • Intermediate/hardn = 27reference
Outcome
Prediction of macroadenoma consistency at surgery by mean ADC, T1WI signal and tumor-to-pons ADC ratio (ADCR)

Performance

As reported in the abstract

ADC · pre-surgical

Further findings

Grade of surgical resection (tumor residue) · post-surgical MRI ≥3 months after surgery

No significant difference in median ADC, ADCR and T1W signal between patients with and without tumor residue

Original publication

Diffusion-weighted imaging does not seem to be a predictor of consistency in pituitary adenomas. Pituitary. Published 25 January 2024. doi:10.1007/s11102-023-01377-6

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