Dietary Macronutrient Composition and Protein Concentration for Weight Loss Maintenance
Authors' conclusion
Maintaining dietary proportional energy from protein, particularly by limiting discretionary food consumption, was associated with reduced energy intake and improved WLM.
Study context
- Population
- Adults who achieved initial weight loss (≥ 5%); 69.8% women; mean age 45 ± 12 years
- Participants
- 1,518 adults
- Outcome
- Changes in body weight, fat mass index (FMI), waist-to-height ratio (WHtR) and hip-to-height ratio (HHtR)
- Follow-up
- 12 months
Methodological details12-month follow-up of the Navigating to a Healthy Weight trial, nutritional geometry approach
- 12-month follow-up of the Navigating to a Healthy Weight trial
- Nutritional geometry approach
Main finding
As reported in the abstract
Mean macronutrient composition: protein
20.6%
Mean macronutrient composition: fat
33.8%
Mean macronutrient composition: carbohydrate
43.1%
Protein energy % vs energy intake, β
−0.33 (−0.39, −0.27) (95% CI)
Observational data: associations, not effects.
Further findings
- Discretionary food, not other food sources, increased energy intake by reducing proportional energy from protein
Original publication
Dietary Macronutrient Composition and Protein Concentration for Weight Loss Maintenance. Obesity (Silver Spring). Published 7 August 2025. doi:10. 1002/ oby. 24370
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