Obesity

Diabetes screening outcomes in youth presenting for paediatric weight management: A report of the Paediatric Obesity Weight Evaluation Registry

Pediatr ObesPublished Prospective registry study

Authors' conclusion

There is discordance between FPG and HbA1c for the diagnosis of prediabetes and DM in youth with obesity. Further studies are needed to understand the predictive capability of these tests for development of DM (in those diagnosed with prediabetes) and cardiometabolic risk.

Study context

Population
Children with obesity without known diabetes mellitus (DM), with concurrent FPG and HbA1c, in POWER; median age 12.0 years (IQR 9.8, 14.6); 48% males; median %BMIp95 134% (IQR 120, 151)
Participants
3,962 children
Exposure
FPG vs HbA1c for diagnosis of prediabetes and DM
Outcome
Rates of prediabetes and DM by FPG and by HbA1c
Methodological detailsmulticentre, 37 multi-component paediatric weight management programs, Data collected prospectively
  • Multicentre
  • 37 multi-component paediatric weight management programs
  • Data collected prospectively

Main finding

As reported in the abstract

Prediabetes and DM rates by screening test

Prediabetes

DM

Observational data: associations, not effects.

Further findings

Discordance between tests by age group

Discordance observed in both age groups: 10-18 years (n = 2915) and 2-9 years (n = 1047)

Original publication

Diabetes screening outcomes in youth presenting for paediatric weight management: A report of the Paediatric Obesity Weight Evaluation Registry. Pediatr Obes. Published 31 January 2024. doi:10.1111/ijpo.13102

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