Diabetes in South Asians: Uncovering Novel Risk Factors With Longitudinal Epidemiologic Data: Kelly West Award Lecture 2023
An erratum to this article was published (Diabetes Care, 1 Apr 2024 ↗)
Authors' conclusion
Longitudinal data with repeat cardiometabolic measures that are supplemented with qualitative and mixed-method approaches enable a deeper understanding of disease risk and resilience factors.
Study context
- Population
- South Asians living in America; original cohort 83% Asian Indian immigrants, expansion to Bangladeshi and Pakistani originoriginal cohort
- Participants
- 1,164 participants
- Exposure
- South Asian Americans vs four other U.S. race and ethnic groups
- Mediators of Atherosclerosis in South Asians Living in America (MASALA)n = 1,164
- Outcome
- Cardiometabolic risk profile vs four other U.S. race and ethnic groups
Methodological detailsMASALA, longitudinal, community-based cohort, MASALA study established in 2010
- MASALA
- Longitudinal
- Community-based cohort
- MASALA study established in 2010
Main finding
As reported in the abstract
- Higher T2D prevalence, lower insulin secretion, more insulin resistance and adverse body composition (higher liver and intermuscular fat, lower lean muscle mass) in South Asian Americans
Observational data: associations, not effects.
Further findings
Diabetes subtypes
- Participants with diabetes more likely to have severe hyperglycemia subtype (β-cell dysfunction, lower body weight), associated with higher incidence of subclinical atherosclerosis
Modifiable factors
- Several modifiable factors incl. diet and physical activity, influenceable via social network members and cultural adaptations
Original publication
Diabetes in South Asians: Uncovering Novel Risk Factors With Longitudinal Epidemiologic Data: Kelly West Award Lecture 2023. Diabetes Care. Published 20 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →