Osteoporosis, bone & mineral

Demographic and clinical differences between individuals with and without DXA scans in Denmark

Osteoporos IntPublished Cross-sectional study

Authors' conclusion

DXA utilization in Denmark increasingly targets individuals at high fracture risk, yet significant gaps persist in secondary fracture prevention.

Study context

Population
Two Danish registry-based cohorts (individuals with fractures and individuals with diabetes, each matched to controls), aged ≥50 years, 2000–2021two cohorts
Exposure
Individuals with a first DXA scan vs matched individuals without a recorded DXA scan
Outcome
Comorbidities, prior fractures, lifestyle-related risk proxies and medication use in DXA scanned vs non-scanned individuals, overall and across time periods (2000-2010 vs 2011-2021)
Methodological detailsnationwide, registry-based, sex- and birth year-matched
  • Nationwide
  • Registry-based
  • Sex- and birth year-matched

Main finding

As reported in the abstract

Characteristics of DXA recipients vs non-scanned
  • DXA recipients were older, more often female, and had a greater burden of comorbidities, prior fractures, and use of centrally acting, cardiovascular, and anti-osteoporotic medications
  • Differences more pronounced in 2011-2021
  • A substantial proportion of individuals with major fractures or users of systemic GC had never undergone DXA
  • 379,686 and 348,980 individuals with DXA and 1,571,452 and 1,736,828 without DXA from the two databases

Observational data: associations, not effects.

Original publication

Demographic and clinical differences between individuals with and without DXA scans in Denmark. Osteoporos Int. Published 26 September 2026. doi:10.1007/s00198-026-08222-z

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