Demographic and clinical differences between individuals with and without DXA scans in Denmark
Authors' conclusion
DXA utilization in Denmark increasingly targets individuals at high fracture risk, yet significant gaps persist in secondary fracture prevention.
Study context
- Population
- Two Danish registry-based cohorts (individuals with fractures and individuals with diabetes, each matched to controls), aged ≥50 years, 2000–2021two cohorts
- Exposure
- Individuals with a first DXA scan vs matched individuals without a recorded DXA scan
- Outcome
- Comorbidities, prior fractures, lifestyle-related risk proxies and medication use in DXA scanned vs non-scanned individuals, overall and across time periods (2000-2010 vs 2011-2021)
Methodological detailsnationwide, registry-based, sex- and birth year-matched
- Nationwide
- Registry-based
- Sex- and birth year-matched
Main finding
As reported in the abstract
Characteristics of DXA recipients vs non-scanned
- DXA recipients were older, more often female, and had a greater burden of comorbidities, prior fractures, and use of centrally acting, cardiovascular, and anti-osteoporotic medications
- Differences more pronounced in 2011-2021
- A substantial proportion of individuals with major fractures or users of systemic GC had never undergone DXA
- 379,686 and 348,980 individuals with DXA and 1,571,452 and 1,736,828 without DXA from the two databases
Observational data: associations, not effects.
Original publication
Demographic and clinical differences between individuals with and without DXA scans in Denmark. Osteoporos Int. Published 26 September 2026. doi:10. 1007/ s00198-026-08222-z
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