Type 2 & other diabetes

Cost-effectiveness of the National Diabetes Prevention Program: A Real-world, 2-Year Prospective Study

Diabetes CarePublished Prospective cohort cost-effectiveness study

Main finding · 2-year total direct medical costsResult — go to the resultAverage reduction $4,552 2020 U.S. dollars 95% CI −13,231 to 2,014

Authors' conclusion

In this real-world population with prediabetes, enrollment in the NDPP was likely to provide cost savings.

Study context

Population
Adults with prediabetes in a large workforce with employer-sponsored health insurance
Participants
5,948 adults
Exposure
National Diabetes Prevention Program (NDPP) enrollment vs nonenrollment
  • NDPPn = 575
  • Nonenrolleesn = 5,373reference
Outcome
2-year total direct medical costs
Follow-up
2 years
Methodological detailsreal-world, difference-in-differences analyses, propensity score weighting, multiple imputation, bootstrapping, health care sector perspective, costs and quality-adjusted life-years (QALYs) discounted at 3% annually, 2020 U.S. dollars
  • Real-world
  • Difference-in-differences analyses
  • Propensity score weighting
  • Multiple imputation
  • Bootstrapping
  • Health care sector perspective
  • Costs and QALYs discounted at 3% annually
  • 2020 U.S. dollars

Main finding

As reported in the abstract

Average reduction

$4,552 2020 U.S. dollars

95% CI −13,231 to 2,014

Observational data: associations, not effects.

Further findings

EQ-5D-5L utility scores and QALYs · 2 years

No difference in EQ-5D-5L utility scores at 2 years or QALYs gained over 2 years, enrollees vs nonenrollees

Uncertainty analyses · 2 years

Probability of saving money with NDPP enrollment
88%
Probability of being cost-effective at willingness-to-pay threshold of $100,000 per QALY gained
84%

Original publication

Cost-effectiveness of the National Diabetes Prevention Program: A Real-world, 2-Year Prospective Study. Diabetes Care. Published 20 November 2024. doi:10.2337/dc24-1110

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