Controlling Nutritional Status (CONUT) score as a key predictor of disability following conservative treatment of osteoporotic vertebral fractures
Main finding · Independent risk factor for disability (ODI > 40%) at 12 months, multivariate analysisResult — go to the resultOdds ratio 1.4 95% CI 1.1–1.9Authors' conclusion
Baseline hospitalization, lower LIV, and higher CONUT scores were associated with disability. Malnutrition was an independent risk factor for disability after OVF.
Study context
- Population
- Patients aged > 60 years with MRI-confirmed osteoporotic vertebral fractures treated conservatively88 analysed after age matching
- Participants
- 173 patients
- Comparison
- Disability vs non-disability
- Disabilityn = 44
- Non-disabilityn = 44reference
- Outcome
- Risk factors for disability (ODI > 40%)
- Follow-up
- 12 months
Methodological detailsmulticentre prospective cohort, matched 1:1 by age, multivariate conditional logistic regression
- Multicentre prospective cohort
- Matched 1:1 by age
- Multivariate conditional logistic regression
Main finding
As reported in the abstract
Independent risk factor for disability (ODI > 40%) at 12 months, multivariate analysis
Odds ratio
1.4
95% CI 1.1–1.9
P = 0.04
Disability (ODI > 40% at 12 months)vs non-disability (ODI ≤ 40%)
OR 1.4 (95% CI 1.1–1.9); P = 0.04
Observational data: associations, not effects.
Further findings
Proportion with disability · 12 months
- Disabled at 12 months among 173 analysed
- 27.7%
Oswestry Disability Index (ODI) course from 3 to 12 months
- Disability group showed worsening ODI, whereas non-disability group improved
Factors compared with non-disability group
- Disability group had lower lumbar indentation value (LIV), higher CONUT scores and more frequent hospitalizations
Original publication
Controlling Nutritional Status (CONUT) score as a key predictor of disability following conservative treatment of osteoporotic vertebral fractures. Osteoporos Int. Published 5 January 2026. doi:10.
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