Continuous Glucose Monitoring Hypoglycemia Alarms in Critical Care: Clinical Utility and Workflow Integration
Authors' conclusion
CGM hypoglycemia signaling integrated into ICU workflows can provide advance warning before hypoglycemic events while maintaining a modest contribution to alarm burden. Signal characteristics influenced nursing response, supporting further optimization of inpatient CGM alarm thresholds and implementation strategies.
Study context
- Population
- Adults in a medical intensive care unit (ICU) using continuous glucose monitoring (CGM) with hypoglycemia signals (low alerts <100 mg/dL, urgent low soon alerts, urgent low alarms <55 mg/dL)
- Participants
- 100 adults
Methodological detailssingle medical ICU
- Single medical ICU
Primary result
As reported in the abstract
CGM hypoglycemia signal frequency, progression, nursing response
- Participants with ≥1 hypoglycemia signal
- 60%
- Total hypoglycemia signals
- 1060
- Signals/patient-day, mean ± SD
- 3.6 ± 6.8
- Signal events after clustering
- 378
- Signal events remaining 80–100 mg/dL, not falling below treatment threshold (<80 mg/dL)
- 51%
- Urgent low alarms preceded by urgent low soon alert
- 95%
- Lead time of urgent low soon alert before urgent low alarm, mean ± SD (min)
- 10.0 ± 7.8
- Confirmatory point-of-care (POC) response time, median (IQR) (min)
- 33 (12-51)
Further findings
Contributors to hypoglycemia (root cause review)
- Most common contributors: IV insulin, carbohydrate coverage and enteral feed-related factors
Original publication
Continuous Glucose Monitoring Hypoglycemia Alarms in Critical Care: Clinical Utility and Workflow Integration. Diabetes Technol Ther. Published 16 September 2026. doi:10.
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