Lipids & metabolic liver disease

Computed tomography-based body composition indicative of diabetes after hypertriglyceridemic acute pancreatitis

Diabetes Res Clin PractPublished Retrospective cohort study

Authors' conclusion

The association between body composition and PPDM-A provides insight into the potential pathogenesis of PPDM-A. Our model is feasible for reliably predicting PPDM-A in the early stages of AP and enables early intervention in patients with potential PPDM-A.

Study context

Population
Patients with hypertriglyceridemic acute pancreatitis (HTGP); 65 with PPDM-A, 100 without
Participants
165 patients
Exposure
Support vector machine (SVM) vs linear discriminant analysis (LDA) vs logistic regression (LR) prediction models for PPDM-A
Outcome
Prediction of post-acute pancreatitis prediabetes/DM (PPDM-A)
Methodological detailsmachine learning prediction model
  • Machine learning prediction model

Main finding

As reported in the abstract

AUC for predicting PPDM-A
GroupAUC
SVM0.796
LDA0.783
LR0.745

AUC

SVM0.796
LDA0.783
LR0.745

Observational data: associations, not effects.

Further findings

Body composition parameters discriminating PPDM-A vs non-PPDM-A

Significant body composition-related parameters, of 84
15

Original publication

Computed tomography-based body composition indicative of diabetes after hypertriglyceridemic acute pancreatitis. Diabetes Res Clin Pract. Published 18 September 2024. doi:10.1016/j.diabres.2024.111862

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