Comorbidity and risk of infection among patients with hip fracture: a Danish population-based cohort study
Authors' conclusion
Comorbidity is an important risk factor for infection up to 1 year after hip fracture surgery.
Study context
- Population
- Patients aged ≥ 65 years undergoing hip fracture surgery in Denmark, 2004–2018
- Participants
- 92,600 patients
- Exposure
- Moderate or severe comorbidity vs no comorbidity
- Outcome
- Any hospital-treated infection
- Follow-up
- 0-30 days and 0-365 days
Methodological detailsDanish population-based medical registries
- Danish population-based medical registries
Main finding
As reported in the abstract
0-30 days
Each group vs noneAdjusted hazard ratio (CI)
Moderate
1.3(1.3–1.4)
Severe
1.6(1.5–1.7)
Observational data: associations, not effects.
Secondary outcomes
| Outcome | None | Moderate | Severe | aHR (CI) | |
|---|---|---|---|---|---|
| Any hospital-treated infection · 0-365 daysModeratevs None | 22% | — not stated in the abstract | 37% | 1.4 (1.4–1.5) | |
| Any hospital-treated infection · 0-365 daysSeverevs None | 1.9 (1.9–2.0) | ||||
| Sepsis · 0-365 daysSeverevs NoneHighest aHR observed | 2.7 (2.4–2.9) | ||||
| 0.20.5125Adjusted hazard ratio (log scale) |
— not stated in the abstract
| Outcome | None | Moderate | Severe |
|---|---|---|---|
| Any hospital- or community-treated infection · 0-365 daysHighest incidence observed | — not stated in the abstract | — not stated in the abstract | 72% |
| Prevalence of comorbidity | — not stated in the abstract | 40% | 19% |
— not stated in the abstract
Original publication
Comorbidity and risk of infection among patients with hip fracture: a Danish population-based cohort study. Osteoporos Int. Published 17 June 2023. doi:10.
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