Clinical impact of acute symptomatic vertebral fractures in the United States: A patient survey and chart review
Authors' conclusion
In this study, pain related to fracture persisted after 24 weeks and affected ADLs
Study context
- Population
- Patients aged ≥ 50 years with ≥ 1 symptomatic osteoporotic vertebral fracture diagnosed within the prior 36 weeks, 7 US clinical sites
- Participants
- 116 patients
- Exposure
- Within 12 weeks vs >12-24 weeks vs >24-36 weeks
- Outcome
- Pain persistence, severity and effect on ADLs during the past 7 days
Methodological detailsobservational, survey and retrospective chart review, multicentre (7 US sites), descriptive analysis
- Observational
- Survey and retrospective chart review
- Multicentre (7 US sites)
- Descriptive analysis
Main finding
As reported in the abstract
Pain severity scores of 7-10
- Constant/steady pain within 12 weeks
- 42%
- Constant/steady pain >24-36 weeks after fracture
- > 20%
- At least intermittent pain >24-36 weeks after fracture
- > 80%
Observational data: associations, not effects.
Further findings
Most common movements increasing pain
- Standing up
- 55%
- Bending down
- 53%
- Lifting
- 42%
- ADLs most impacted were housework and walking
Original publication
Clinical impact of acute symptomatic vertebral fractures in the United States: A patient survey and chart review. Osteoporos Int. Published 25 March 2026. doi:10.
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