Climate Vulnerability Index and Incident Type 2 Diabetes in a Large Integrated Health Care System
Main finding · Incident T2DResult — go to the resultAdjusted hazard ratio 1.23 95% CI 1.11–1.36Authors' conclusion
In this cohort study of 1 003 526 adults, higher community CVI was associated with greater risk of incident T2D independently of traditional risk factors. Linking geocoded CVI to electronic health records may support targeted prevention, risk stratification, and population health planning.
Study context
- Population
- Adults aged ≥18 years without T2D at baseline, with ≥1 outpatient encounter and ≥1 subsequent encounter, June 2016–August 2023, Houston Methodist Learning Health System Registry (Greater Houston, Texas); mean age 50.9 years, 60.4% women
- Participants
- 1,003,526 adults
- Exposure
- Highest vs lowest census tract-level Climate Vulnerability Index (CVI) quartile
- Outcome
- Incident T2D identified by diagnosis codes, antihyperglycemic prescriptions, or HbA1c 6.5% or higher
Methodological detailssingle integrated health system registry
- Single integrated health system registry
Main finding
Incident T2D
Adjusted hazard ratio
1.23
95% CI 1.11–1.36
By group
Q4vs Q1
aHR 1.23 (95% CI 1.11–1.36)
As reported in the abstract
Observational data: associations, not effects.
Further findings
7-year risk of T2D
Overall T2D incidence
- Developed T2D over 2.1 million person-years
- 40 152
- Overall incidence, cases per 100 person-years
- 1.88
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Climate Vulnerability Index and Incident Type 2 Diabetes in a Large Integrated Health Care System. JAMA Netw Open. Published 1 December 2025. doi:10. 1001/ jamanetworkopen. 2025. 47119
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