Characteristics of Nocturnal Hypoglycaemic Events and Their Impact on Glycaemia
Authors' conclusion
The results showed that nocturnal hypoglycaemic events are a common occurrence in persons with type 1 diabetes using MDI with significant differences between the characteristics of nocturnal and diurnal events.
Study context
- Population
- People with T1D using multiple daily injections (MDI) therapy
- Participants
- 185 people
- Exposure
- Nocturnal vs diurnal periods
- Outcome
- Incidence of hypoglycaemic events <70 mg/dl
Methodological detailsContinuous glucose monitoring (CGM) data under everyday conditions, up to 13 weeks
- CGM data under everyday conditions
- Up to 13 weeks
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Duration of hypoglycaemic events <70 mg/dl
Time below range (TBR), TB54 and incidence of events <54 mg/dl
- Not significantly different between night and day
Duration of hypoglycaemic events <70 mg/dl
- Nocturnal events significantly longer and enveloped by less rapidly changing glucose levels
Glycaemia on days following nights with hypoglycaemic events
- Decrease in time above range (TAR), mean CGM glucose and morning glucose; increase in TB54, TBR and coefficient of variation (CV)
Original publication
Characteristics of Nocturnal Hypoglycaemic Events and Their Impact on Glycaemia. J Diabetes Sci Technol. Published 19 August 2024. doi:10.
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