Characteristics and treatment options of 272,152 geriatric patients with very high and high fracture risk
Authors' conclusion
The majority of geriatric patients is at a very high-risk for osteoporotic fractures, characterized by cognitive impairment, ADL limitations, and increased vulnerability. While some patients had contraindications, most were eligible for anti-osteoporotic and particularly bone anabolic treatments.
Study context
- Population
- Geriatric patients in the Geriatrics in Bavaria-Database, 2013–2023 (mean age 82 ± 7 years)
- Participants
- 272,152 patients
- Exposure
- Very high-risk vs High-risk
- Outcome
- Proportion of geriatric patients at high and very high fracture risk, their characteristics, and share with contraindications to specific anti-osteoporotic treatments
Methodological detailsregistry database analysis (Geriatrics in Bavaria-Database (GiB-DAT))
- Registry database analysis (GiB-DAT)
Main finding
As reported in the abstract
Eligibility for specific anti-osteoporotic treatment
Very high-risk
54%
- Patients qualifying for specific anti-osteoporotic treatment
- > 75%
- Contraindications for bone anabolic treatment, women
- 20%
- Contraindications for bone anabolic treatment, all very high-risk patients
- 8%
- No contraindication for any specific anti-osteoporotic medication, total population
- 70%
Observational data: associations, not effects.
Further findings
| Outcome | Very high-risk |
|---|---|
| Characteristics: MMSE and ADL scores (lowest in very high-risk group) | 23 ± 5 points |
| ADL score | 45 ± 20 points |
Original publication
Characteristics and treatment options of 272,152 geriatric patients with very high and high fracture risk. Osteoporos Int. Published 30 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →