Characteristics and Risk of Diabetes in People With Rare Glucose Response Curve During an Oral Glucose Tolerance Test
Main finding · Diabetes onsetResult — go to the resultHazard ratio 0.30Authors' conclusion
People with lower 30-minute PG than fasting PG tended to be women, young, healthy, and at low risk of diabetes onset.
Study context
- Population
- Japanese general population without diabetes, 3995 men and 3500 women, mean age 56.7 years3,897 analysed prospectively
- Participants
- 7,495 participants
- Exposure
- Oral glucose tolerance test (OGTT) glucose response curve groups: Plasma glucose (PG) at 30 min < fasting PG (group 3) and PG at 30 min ≥ fasting PG with PG at 60 min < fasting PG (group 2) vs PG at 30 and 60 min ≥ fasting PG (group 1)
- Group 1n = 6,552reference
- Group 2n = 769
- Group 3n = 174
- Outcome
- Diabetes onset
- Follow-up
- Mean 5.8 years
Methodological detailspopulation-based
- Population-based
Main finding
As reported in the abstract
Hazard ratio
0.30
- Developed diabetes among 3897 participants analyzed prospectively
- 434
Observational data: associations, not effects.
Further findings
Characteristics by group
- Group 3 glucose response curve was boat shaped
- Group 3 had the youngest age, lowest percentage of men and best health condition, followed by groups 2 and 1
Original publication
Characteristics and Risk of Diabetes in People With Rare Glucose Response Curve During an Oral Glucose Tolerance Test. J Clin Endocrinol Metab. Published 1 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →